With the help of an ancient Kryptonian power, Lex Luthor unites the world’s Super-Villains to capture all of Earth's Super Heroes, until…only the DC Super Hero Girls are left to stop the Legion of Doom. Our heroes must cross dimensions to rescue their fellow Super Heroes from the Phantom Zone, but a fortuitous wrong turn leads them to Titans Tower – where they find much-needed allies in the Teen Titans!
Teen Titans Go! & DC Super Hero Girls: Mayhem in the Multiverse is a 2022 direct-to-video animated superhero comedy film and a crossover between the television series Teen Titans Go! and DC Super Hero Girls, which is adapted from the DC Comics superhero team of the same name, and the DC Super Hero Girls franchise. It is the first DC Super Hero Girls film in four years since 2018's DC Super Hero Girls: Legends of Atlantis, and the first one to center on the 2019 incarnation. It was released on DVD and Blu-ray on May 24, 2022, followed by a premiere on Cartoon Network on May 28. The film also served as the fourth Teen Titans Go! film, following Teen Titans Go! To the Movies, Teen Titans Go! vs. Teen Titans, and Teen Titans Go! See Space Jam, and also served as the series finale of the DC Super Hero Girls TV series.